Evolution of SARS-CoV-2 variants and their impact on the epidemic period in Villa Clara, Cuba
1 Department of Molecular Biology, Provincial Center of Hygiene, Epidemiology and Microbiology of Villa Clara (PCHEM), Cuba.
2 Department of Virology, “Pedro Kourí" Institute of Tropical Medicine (IPK), Cuba.
3 EurAsia Heart Foundation, Switzerland.
4 Department of Hygiene and Epidemiology, Faculty of Health Technology and Nursing (FHTN), University of Medical Sciences of Villa Clara (UMS-VC), Cuba.
Research Article
Open Access Research Journal of Multidisciplinary Studies, 2024, 08(02), 116-125.
Article DOI: 10.53022/oarjms.2024.8.2.0071
Publication history:
Received on 04 November 2024; revised on 17 December 2024; accepted on 19 December 2024
Abstract:
Epidemiological and clinical aspects of COVID-19 are modified according to the variant circulating, hence the importance of identifying the variables in each epidemic period. The objective of the research consisted in characterizing the evolution of SARS-CoV-2 variants, and its repercussion in the epidemic period in Villa Clara province, Cuba. A cross-sectional descriptive observational study was carried out in the Laboratory of Molecular Biology of Villa Clara, in the period from December 2020 to May 2023. In the province, the epidemic period was divided into three, in the first one, the circulation of D614G was detected; in the second one, the one with the highest incidence and mortality, the beta and delta variants were identified, and in the third one, omicron and its sublineages were sequenced. It is concluded that in Villa Clara the D614G, beta, delta and omicron variants were the ones that originated the epidemic waves. The most intense epidemic period was concentrated in four months, from July to October 2021. The responsibility for this high incidence and mortality was attributed to the beta and delta variants, without being able to specify whether it was one or both of them.
Keywords:
Coronavirus infections; Genetic variants; SARS-CoV-2; Villa Clara
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