Appraisal the toxicity of CaO and Gold Nanoparticles in Wistar rats: A systematic review
1 Department of Basic Science, Faculty of Dentistry, University of Kufa, Al-Najaf, Iraq.
2 College of Dentistry and Oral Surgery, Alasmarya University.
Review
Open Access Research Journal of Multidisciplinary Studies, 2025, 09(01), 001-–009.
Article DOI: 10.53022/oarjms.2025.9.1.0074
Publication history:
Received on 20 November 2024; revised on 05 January 2025; accepted on 08 January 2025
Abstract:
Nanotechnology is a new science and these risks are not realistically defined or observed at present. Among these risks is that particles with a diameter of 300 nanometers or smaller can with no trouble penetrate the human body also penetrate cells, as well as that particles with a diameter of 70 nanometers or smaller can easily enter the nucleus of the cell. It is possible to imagine the potential danger to the body, as an interaction may occur between nanoparticles. Because of the small size of nanoparticles, masks and even protective masks of all types are not useful for protection against them, as these particles can penetrate them. The actual impact of nanoparticles on liver and kidney function otherwise male fertility and toxicity is assessed afterward a careful investigation of the obtainable literature. The chief role reviews animal patterns to comprehend the biomarkers related to the function of the liver and kidneys, also testis function of nanoparticles. Our principal outcomes put forward that nanoparticles are in general capable to reach the liver, kidneys, and the testicle in minor quantities where they persevere for more than a few months, nevertheless of the route of exposure. Notable, the majority of nanoparticles have little shortest toxicity to liver, kidneys, and the testis. Research conducted on mice and laboratory animals has shown that nanoparticles, after entering their bodies, tend to migrate and localize in the liver, kidney and that these particles can penetrate to reproductive system, and nanoparticles can also localize in other organs.
Keywords:
Nanotechnology; Toxicity; Silver; Systematic Review
Full text article in PDF:
Copyright information:
Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0