Regenerative medicine and stem cells: A new frontier in healthcare
1 Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, 781026.
2 Royal School of Pharmacy, The Assam Royal Global University-NH-37, opp. Tirupati Balaji Temple, Betkuchi, Guwahati 781035, Assam, India.
Review
Open Access Research Journal of Life Sciences, 2025, 09(01), 032-039.
Article DOI: 10.53022/oarjls.2025.9.1.0025
Publication history:
Received on 27 December 2024; revised on 26 February 2025; accepted on 01 March 2025
Abstract:
A groundbreaking development in contemporary medicine, stem-cell therapy has the potential to revolutionize the way many crippling diseases and injuries are treated. This review explores the cutting edge of stem cell-based therapies, emphasizing the unique potential of stem cells to differentiate into a wide range of phenotypes through specialized cell differentiation and regeneration. By exploring the procedures, uses, and difficulties involved in applying stem cells across several medical specialties, this study seeks to assist researchers, doctors, and stakeholders in navigating the complex field of stem-cell treatment. Massive advances in medical science have been made possible by the historical progression from fundamental contributions in the late 19th and early 20th centuries to more recent discoveries like ESC separation and iPSC discovery. The regenerative potential of stem cells extends throughout the embryonic, adult, induced pluripotent, and perinatal phases, providing previously unheard-of therapeutic prospects in the treatment of tissue damage, cancer, neurodegenerative diseases, cardiovascular conditions, spinal cord injuries, and diabetes. However, challenges including cancer, immunological rejection, and precise control of stem-cell behaviour call for thorough investigation and creative solutions. This publication offers a comprehensive overview of the successes, challenges, and future directions in stem cell-based regenerative medicine by summarizing current biotechnological developments, critical trial evaluations, and upcoming technologies. A roadmap for stem cell treatment is provided by future directions such as immune modulation tactics, precision medicine integration, gene-editing technology breakthroughs, and bioengineering synergy. The emphasis on the potential of stem-cell therapy underscores its noteworthy impact on modern medicine and suggests a future where customized regenerative therapies will treat a range of illnesses.
Keywords:
Regenerative Medicine; Stem-Cell Therapy; Neurodegenerative Disorders; Immunological Rejection; Gene-Editing Technologies; Precision Medicine
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Copyright © 2025 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0