Synthesis of Schiff Bases from Triazines

Heshw nozad yousif *, Bekhal Omer Mohammed and Muthanna M. AWAD

Department of Chemistry, College of Science, University of Kirkuk, Kirkuk, Iraq.
* Corresponding Author
 
Research Article
Open Access Research Journal of Chemistry and Pharmacy, 2026, 09(01), 055–068.
Article DOI: 10.53022/oarjcp.2026.9.1.0025
Publication history: 
Received on 10 July 2026; revised on 16 August 2026; accepted on 18 August 2026
 
Abstract: 
This review summarizes the chemistry, synthesis, applications, and characterization of triazine-derived Schiff bases, with emphasis on the integration of the 1,3,5-triazine core with azomethine (C=N) functionalities. The principal synthetic strategies include the use of amino-functionalized triazines such as melamine, aldehyde-functionalized triazine cores, and imine-linked covalent organic frameworks. Biological and pharmaceutical activity, heavy-metal sensing, corrosion-related surface interactions, fluorescence, bioimaging, and optoelectronic applications are discussed in relation to the structural features of the triazine and Schiff-base units. The review also highlights advanced synthetic approaches, including microwave-assisted, one-pot, and solvothermal methods, which can reduce reaction time and solvent consumption while enabling access to structurally complex products and crystalline frameworks. Finally, the main spectroscopic and physical characterization methods used for structural confirmation are outlined, including FTIR, NMR, elemental analysis, mass spectrometry, TGA, and DSC. Overall, triazine-derived Schiff bases represent versatile molecular and framework systems with broad potential in coordination chemistry, sensing, biological applications, and functional materials.
 
Keywords: 
 Triazine – derived Schiff bases; Azomethine (C=N) chemistry; Covalent organic frameworks; Heavy – metal sensing; Microwave – assisted synthesis; Spectroscopic characterization. 
 
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